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American journal of cardiovascular drugs : drugs, devices, and other interventions

An increase in the level of free oxygen radicals may cause mutagenicity, cytotoxicity, and changes in gene expression, leading to the development of malignant tumors, and this mutagenicity may contribute to the transformation of benign development into malignant [41]

Some of the secondary gains are enhanced muscle mass and lean body composition, which can increase libido and sexual performance

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These include impact of NAD + precursors on chemotherapy induced peripheral neuropathy (Hamity et al, 2020), hearing loss (Kim et al, 2014), and renal toxicity (Guan et al, 2017)